Bio-101 - Improve Research Reproducibility

Statistical analysis

Author: Adam Yala
Date: Jun 1, 2021，Views：875

Original protocol used in research article：

Toward robust mammography-based models for breast cancer risk
Science Translational Medicine, Jan 27, 2021; DOI: 10.1126/scitranslmed.aba4373

T cell isolation

Authors: Hasan Zaki, Yang-Xin Fu and Chuanhui Han
Date: Jun 1, 2021，Views：988

Original protocol used in research article：

The AIM2 and NLRP3 inflammasomes trigger IL-1\–mediated antitumor effects during radiation
Science Immunology, May 6, 2021; DOI: 10.1126/sciimmunol.abc6998

Immune memory assessment

Authors: Kai Yang and Zhuang Liu
Date: Jun 1, 2021，Views：873

Original protocol used in research article：

Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer
Science Advances, Aug 13, 2020; DOI: 10.1126/sciadv.aba3546

Confocal microscopy and image analysis

Authors: Jan N Hansen, Fabian Kaiser, Florian I Schmidt and Dagmar Wachten
Date: Jun 1, 2021，Views：969

Original protocol used in research article：

Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium
eLife, Jun 24, 2020; DOI: 10.7554/eLife.57907

PCR amplification and next generation sequencing of sgRNAs

Authors: Xiangbing Qi and Ting Han
Date: May 31, 2021，Views：1021

Original protocol used in research article：

Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
eLife, Aug 17, 2020; DOI: 10.7554/eLife.59994

Data analysis for genome-wide CRISPR knockout screening

Authors: Xiangbing Qi and Ting Han
Date: May 31, 2021，Views：913

Original protocol used in research article：

Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
eLife, Aug 17, 2020; DOI: 10.7554/eLife.59994

Co-immunoprecipitation of CCNK and DDB1 with 3xFLAG-CDK12 complex

Authors: Longzhi Cao, Xiangbing Qi and Ting Han
Date: May 31, 2021，Views：930

Original protocol used in research article：

Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
eLife, Aug 17, 2020; DOI: 10.7554/eLife.59994

Remodeling of the spleen tissue

Authors: Lintao Wang, Junfeng Zhang, Chunming Wang and Lei Dong
Date: May 31, 2021，Views：868

Original protocol used in research article：

Transforming the spleen into a liver-like organ in vivo
Science Advances, Jun 9, 2020; DOI: 10.1126/sciadv.aaz9974

Purification of DDB1ΔBPB

Author: Longzhi Cao
Date: May 31, 2021，Views：969

Original protocol used in research article：

Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation
eLife, Aug 17, 2020; DOI: 10.7554/eLife.59994

Metabolomic analysis

Authors: Shenglin Luo, Yang Wang and Chunmeng Shi
Date: May 30, 2021，Views：875

Original protocol used in research article：

Near-infrared oxidative phosphorylation inhibitor integrates acute myeloid leukemia\–targeted imaging and therapy
Science Advances, Dec 31, 2020; DOI: 10.1126/sciadv.abb6104

实验方法 

Request a Protocol

提交 

关于