Bio-101 - Improve Research Reproducibility

Subcellular fractionation

Authors: Tyler B Faust and Alan D Frankel
Date: Feb 22, 2021，Views：854

Original protocol used in research article：

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
eLife, May 30, 2018; DOI: 10.7554/eLife.31879

Sequences, plasmids, transfection and RNA interference

Author: Zhou Yu
Date: Feb 22, 2021，Views：829

Original protocol used in research article：

Lys29-linkage of ASK1 by Skp1−Cullin 1−Fbxo21 ubiquitin ligase complex is required for antiviral innate response
eLife, Apr 11, 2016; DOI: 10.7554/eLife.14087

Immune signature, immune infiltration, and nontumor fraction

Authors: Yue Wang and Da Yang
Date: Feb 22, 2021，Views：828

Original protocol used in research article：

LincRNA-immunity landscape analysis identifies EPIC1 as a regulator of tumor immune evasion and immunotherapy resistance
Science Advances, Feb 9, 2021; DOI: 10.1126/sciadv.abb3555

Bisulfite sequencing and TAB sequencing

Authors: Gerd P. Pfeifer and Zhijun Huang
Date: Feb 22, 2021，Views：839

Original protocol used in research article：

The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins
Science Advances, Jan 20, 2021; DOI: 10.1126/sciadv.abb9149

Synthesis of FX and preparation of FX@HP

Authors: Minjie Sun and Zhaoting Li
Date: Feb 22, 2021，Views：848

Original protocol used in research article：

Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti–PD-L1 immunotherapy
Science Advances, May 14, 2020; DOI: 10.1126/sciadv.aaz9240

Procurement and treatment of human cartilage

Author: Fadia Kamal
Date: Feb 22, 2021，Views：847

Original protocol used in research article：

Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis
Science Translational Medicine, Feb 9, 2021; DOI: 10.1126/scitranslmed.aau8491

Animal studies

Author: Fadia Kamal
Date: Feb 22, 2021，Views：867

Original protocol used in research article：

Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis
Science Translational Medicine, Feb 9, 2021; DOI: 10.1126/scitranslmed.aau8491

Preparation of lymph node stromal cells

Authors: Christian Perez-Shibayama and Burkhard Ludewig
Date: Feb 22, 2021，Views：780

Original protocol used in research article：

Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8+ T cells
Science Immunology, Sep 11, 2020; DOI: 10.1126/sciimmunol.abb7066

Epidemiological, demographic and geographical data

Author: Huaiyu Tian
Date: Feb 21, 2021，Views：944

Original protocol used in research article：

An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Science, May 7, 2020; DOI: 10.1126/science.abb6105

Human mobility data

Author: Huaiyu Tian
Date: Feb 21, 2021，Views：963

Original protocol used in research article：

An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Science, May 7, 2020; DOI: 10.1126/science.abb6105

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